Novel annotated Patient-Derived tumor Xenografts (PDX) propagated in immunodeficient mice and Organoids (PDO) in Matrigel have become essential models to study inter- and intra-tumor heterogeneity, ...
Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...
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