A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation. The reformulation of a 100-mg tablet into a 300-mgtablet ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Although physicochemical preformulation screening is practised universally within the pharmaceutical industry, physicomechanical screening is applied to a lesser extent and often only where a problem ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...