Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

In a recent study posted to the bioRxiv* pre-print server, researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the ...

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators ...

In autosomal-dominant AD, mutation type influenced amyloid-PET pegged to estimated years before symptom onset. Some mutations came with more striatal amyloid; some with cortical. CSF Aβ42 did not vary ...