In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

One of the most important milestones in modern science, does April 25 also mark the date of an intellectual heist? As has been well-documented, a third person contributed to the discovery — the ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Beef jerky and some woolly mammoths have at least one thing in common: Drying turns their DNA into super-tough glass. This glassy DNA is so stable that it preserved the three-dimensional structure of ...

James Watson, a renowned molecular biologist and one of the Nobel Prize winners for discovering the structure of DNA, died Thursday after a brief illness, according to a statement from his former ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.