AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...

Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements vital for its ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

Doubly stapled α-helix consisting only of achiral amino acids. Its one-handed form can be isolated because the interconversion between the right- and left-handed forms is almost completely suppressed.

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

The 2024 Nobel prize in chemistry has been awarded to David Baker, Demis Hassabis and John Jumper for their work on understanding the structure of proteins, which play vital roles in all living ...

Researchers have identified a previously unknown bacterial protein, the structure of which is being used in the design of protein nanoparticles for the targeted delivery of anticancer drugs to tumors.