Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...
LA JOLLA, CA—Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, ...
Scientists at the Baylor College of Medicine say they have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called ...
Master the principles of MS/MS in proteomics to improve peptide sequencing accuracy. This guide covers fragmentation methods, ...
A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...
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New insights into how a molecular gatekeeper controls early protein modification
For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...
Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...
A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS) in regulating the tumor microenvironment (TME) and driving cancer progression. The study ...
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