Isoforms of the PDE4 family of cAMP-specific phosphodiesterases (PDEs) are expressed in a cell type-dependent manner and contribute to underpinning the paradigm of intracellular cAMP signal ...
New research in this week’s Journal of Neuroscience sustains hopes of boosting cognition through enhancement of the cyclic AMP (cAMP) signaling pathway that turns on memory genes. Using genetic and ...
Pharmacological inhibition of type 4 cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase (PDE4) produces antidepressant-like effects in animals; however, it is not known which of the four ...
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