The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...

Stable isotopes are increasingly being used to unlock the wealth of information contained in specimens preserved in museum collections. However, preservation methods that employ formalin may confound ...

For decades, formalin-fixing paraffin-embedding has been the preferred method for preserving biological samples for diagnostic research. Formalin is relatively inexpensive and can be used to preserve ...

Collect tissues using sharp scissors or scalpel blades and mouse-tooth forceps. Handle tissues gently. Grasp and cut samples at the edges, so the areas of interest aren't damaged. At right is a ...

As technologies and methodologies advance, so do the potential applications for biospecimens. In this article, we explore seven uses of FFPE, ranging from the common to the cutting-edge.

Today, clinical decisions regarding cancer therapy are largely informed by histologic evaluation and perhaps analysis of select molecular biomarkers associated with the particular tumor. However, ...