Formalin-fixed paraffin-embedded (FFPE) tissues have long served as invaluable resources in biomedical research, particularly in clinical and translational studies. Despite the inherent challenges ...
RNA and DNA extraction kits take formalin-fixed tissue samples by storm, enabling superior quality and yields. Researchers using standard extraction protocols that heat samples to eliminate ...
The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...
Autopsy brain tissue should be sent half fixed (in 10% buffered formalin for 2 weeks) and half frozen in a -80°C freezer (or, lacking that, in a -20°C freezer). Do NOT treat whole brains in formic ...