The authors explain a process for moisture-activated dry granulation in detail and provide guidance for the selection of excipients and equipment. In the pharmaceutical industry, the three most common ...

Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...