As far back as Plato and Aristotle, people believed that our memories had to be physical somethings that were stored somewhere in the brain. But only in modern times have we learned much about what ...

The hippocampus serves as the primary learning and memory center of the brain, but this is not where our memories are held. Rather, memory traces or engrams are represented by the connections between ...

LA JOLLA, CA – Using cutting-edge genetic tools, 3D electron microscopy, and artificial intelligence, Scripps Research scientists and colleagues have uncovered key structural hallmarks of long-term ...

Dynamic mechanisms of engram maturation. During the allocation, engram allocation is primarily governed by enhancements in intrinsic neuronal excitability, driven primarily by increased ...

Sheena Josselyn discussed how she uses optogenetic tools to bias, express, and erase memories in mice. Shortly before we trained mice to associate a context with an aversive foot shock, we activated ...

A study published in Nature by researchers at Baylor College of Medicine changes the way we understand memory. Until now, memories have been explained by the activity of brain cells called neurons ...

Despite advances in understanding how memories are formed and stored, the retrieval of memories after death remains an elusive and complex challenge. Memory formation is one of the most intricate ...