Objective: Newborns are highly susceptible to bacterial sepsis. Mannan-binding lectin (MBL), M-, L- and H-ficolin recognize microorganisms and activate the complement system via MBL-associated serine ...

The history of therapeutic interventions in clinical trials for sepsis has been referred to as the "graveyard for pharmaceutical companies." That is now set to change, as research provides hope for ...

Sepsis is a life-threatening medical condition that triggers an uncontrolled inflammatory reaction and is caused by the entry of various microorganisms into the human bloodstream. Sepsis is mainly ...

Drawing from research on sepsis and complement biology, they developed the monoclonal antibody vilobelimab to block overactive inflammatory responses in patients with severe inflammatory diseases ...

Sepsis is the deadliest and most expensive condition treated in hospital critical care units, with septic shock carrying a 34% mortality rate. Early sepsis detection is critical to saving lives and ...

"The first hurdle is knowledge-based: knowing a patient experienced a recent sepsis diagnosis and sepsis hospitalization," says Benjamin A. Zaniello, MD, MPH. Editor’s note: The following Q&A resulted ...

Sepsis is a condition in which the body responds improperly. More specifically, the infection causes the organs in the body to shut down. This is a serious illness which could lead to extremely low ...