The genetic code is the recipe for life, and provides the instructions for how to make proteins, generally using just 20 amino acids. But certain groups of microbes have an expanded genetic code, in ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Scientists trying to engineer biologic molecules with new functions have long felt limited by the 20 amino-acid building blocks. Researchers are working to develop ways of putting new building ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Starting from the four innermost letters and working to the outermost ring, this table shows shows which three-letter base sequence or codon encodes which amino acid. In the journal Angewandte Chemie ...

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words. But researchers trying to ...